ABout US

Computational chemists. Drug designers. Paradigm changers.
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Core Tenets of Nimbus’ Mission

  • Medicines are our mission.
  • We are building a great company that will make important contributions to human health and provide value to our investors and collaborators.
  • Our focus is unmet medical need and high-value targets in the metabolism-oncology-immunology triad.
  • Nimbus is fully committed to computational chemistry and the symbiotic relationship with our co-founder, Schrödinger, and continues to build and partner to establish new capabilities that advance drug discovery and development.
  • Our company is capable of moving novel medicines to registration, but will also be willing to partner when appropriate.

board of directors

Bruce Booth, Ph.D.

Chairman of the Board
Partner, Life Sciences
Atlas Venture

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Chris Christoffersen, Ph.D.

General Partner
Lightstone Ventures

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Ramy Farid, Ph.D.

President & CEO
Schrödinger

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Rajeev Dadoo, Ph.D., MBA

Partner
SR One Ltd.

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Steve Hall, Ph.D.

General Partner
Lilly Ventures

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Mark Iwicki

Chairman and CEO
Kala Pharmaceuticals

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Nikola Trbovic, Ph.D.

Executive Director, WRD and Principal
Pfizer Ventures

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Jeb Keiper, M.S., MBA

CEO
Nimbus Therapeutics

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George P. Vlasuk, Ph.D.

President and CSO
Navitor Pharmaceuticals

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SCIENTIFIC ADVISORS & COLLABORATORS

Metabolic Diseases/NASH
  • Arun Sanyal, M.D.Virginia Commonwealth University
  • Scott Friedman, M.D.Mt. Sinai Hospital
  • Stephen Harrison, M.D.Brooke Army Medical
  • Brent Tetri, M.D.St. Louis University
  • Rohit Loomba, M.D.UC San Diego
  • Tom Hughes, Ph.D.Zafgen, Novartis
Oncology
  • Lou Staudt, M.D., Ph.D.National Cancer Institute
  • Jennifer Brown, M.D., Ph.D.Dana-Farber Cancer Institute
  • Reuben Shaw, Ph.D.Salk Institute
  • Bryan C. Fuchs, Ph.D.Massachusetts General Hospital
  • Kenneth Kenji Tanabe, M.D.Massachusetts General Hospital
  • A. Thomas Look, M.D.Dana-Farber Cancer Institute
  • David Tuveson, M.D., Ph.D.Cold Spring Harbor Laboratory
Inflammation
  • Robert A. Lewis, M.D.Aventis, Syntex (retired)
  • Luke O’Neill, Ph.D.University College Dublin
  • Xiaoxia Li, Ph.D.Cleveland Clinic
  • David A. Fruman, Ph.D.UC Irvine
  • Robert Inman, M.D.University of Toronto

Investors

Nimbus Therapeutics is backed by world-class life science investors, including Atlas Venture, SR One, Lilly Ventures, Bill Gates, Pfizer Venture Investments and Lightstone Ventures. The company closed a $24 million Series A financing in June 2011, a $43 million Series B financing in March 2015, and an additional $65 million in financing in June 2018.

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Bruce Booth, Ph.D.

Chairman of the Board
Partner, Life Sciences
Atlas Venture

Bruce Booth is a partner and focuses on the discovery and development of novel medicines and therapeutic platforms. Bruce is currently chairman of AVROBIO (NASDAQ:AVRO), Kymera Therapeutics, Hotspot Therapeutics, Nimbus Therapeutics, Rodin Therapeutics, and Unum Therapeutics (NASDAQ:UMRX), and also serves on the boards of Lysosomal Therapeutics and Magenta Therapeutics (NASDAQ:MGTA). He previously served on the boards of past Atlas companies Avila (acquired by Celgene), Padlock (acquired by BMS), Prestwick (acquired by Biovail), Stromedix (acquired by Biogen), Zafgen (NASDAQ:ZFGN), and a number of other ventures. Bruce serves as an advisor in various capacities to UCB, Takeda, and the Gates Foundation. He also serves on the boards of the National Venture Capital Association, the Pennsylvania State Research Foundation, and New England Disabled Sports, a charity dedicated to adaptive sports. Bruce blogs about biotech and venture capital topics at LifeSciVC.com, which is syndicated on Forbes. Prior to joining Atlas in 2005, Bruce was a consultant at McKinsey & Company, as well as an investor for Caxton Health Holdings. As a British Marshall Scholar, Bruce received a D.Phil. (Ph.D.) in molecular immunology from Oxford University. He received a B.S. in biochemistry, summa cum laude, from The Pennsylvania State University. Bruce enjoys running, skiing, hiking, and fly fishing. He lives in Wellesley, MA and has three wonderful kids.

Chris Christoffersen, Ph.D.

General Partner
Lightstone Ventures

Dr. Chris Christoffersen is a General Partner of Lightstone Ventures. He focuses on biopharmaceutical investments out of the firm’s Boulder, CO, office. Chris joined Morgenthaler in 2001 and serves as a General Partner. His signature deals include Avidia (acquired by Amgen in 2006), Threshold (NASDAQ: THLD), Morphotek (acquired by Easai in 2007), and FoldRx (acquired by Pfizer in 2010). He serves on the boards of Catalyst BioSciences, Galleon Pharmaceuticals, Tragara Pharmaceuticals, Stemgent, Elcelyx, and Nimbus Therapeutics. Chris brings to Lightstone more than 20 years of operations experience, having served as CEO and President of Ribozyme Pharmaceuticals (a/k/a Sirna Therapeutics; acquired by Merck for $1.2B), Senior Vice President of Research at SmithKline Beecham, Vice President of Discovery Research at The Upjohn Company, and President of Colorado State University.

Chris is a recognized thought leader in the field of biotechnology. He received an honorary doctor of law degree from Cornell College in 1983, the Outstanding Research of Year Award from the International Society of Quantum Biology in 1981, the W. E. Upjohn Award for contributions in biotechnology in 1988, and a Lifetime Achievement Award in 2003 from the Colorado Biosciences Association.

Ramy Farid, Ph.D.

President & CEO
Schrödinger

Dr. Ramy Farid joined Schrödinger in 2002 and serves as President & CEO and as a member of the board of directors. Prior to joining Schrödinger, Ramy was an Assistant Professor in the Chemistry Department at Rutgers University. He was an NIH Postdoctoral Fellow in the Department of Biochemistry and Biophysics at the University of Pennsylvania and received his Ph.D. in Chemistry from Caltech.

Rajeev Dadoo, Ph.D., MBA

Partner
SR One Ltd.

Rajeev joined SR One in 2004 and is an alum of the Kauffman Fellows Program.  His prior and current investments include Adheron, iPierian, True North, Propeller Health, Concert Pharmaceuticals, CyDex Pharmaceuticals, NeuroTherapeutics Pharma, Tranquis Therapeutics, IlluminOss Medical and Avhana Health. Rajeev also spent time with GSK's competitive excellence group, where he worked on company-wide strategic projects and operational projects. Prior to SR One, Rajeev worked at Genentech, where his role included technology and clinical development, and at Bio-Rad Laboratories in a product development role. In addition, Rajeev has worked in business development at Genome Therapeutics and was a co-founder of Unimicro Technologies. Rajeev received his B.A. in chemistry and mathematics from Knox College, his MBA from the Wharton School of the University of Pennsylvania and his Ph.D. in chemistry from Stanford University.

Steve Hall, Ph.D.

General Partner
Lilly Ventures

Dr. Steve Hall brings more than 25 years of pharmaceutical experience from both multinational pharmaceutical companies and biotech organizations to Lilly Ventures. Prior to joining Lilly Ventures, Steve was the co-founder and Senior Vice President, Research and Development, at Serenex, Inc. There, he recruited and led a team in developing a novel discovery technology and applied it to a project that advanced from a novel screen to first patient dosed in just over three years. This novel, orally-active Hsp90 inhibitor was the subject of strong interest across the industry and led to the acquisition of Serenex by Pfizer in April 2008. Prior to joining Serenex, Steve was Site Director, Sphinx Labs, Eli Lilly, where he oversaw lead generation efforts in the areas of combinatorial chemistry, automation, high-throughput screening, biomolecular research and information technology. There, he was a key member of a small team that developed and executed a strategy to partner Lilly’s expertise in high-throughput chemistry with three Japanese pharmaceutical companies with an aggregate value of more than $75 million. Steve currently sits on the boards of FORMA Therapeutics, Hydra Biosciences, InnoCentive, Nimbus Therapeutics and Cerulean Pharma. He also is a board observer at Avid Radiopharmaceuticals and Viamet.

Steve is the author of more than 40 papers and 60 papers and 60 patients. He received his B.S. in Chemistry from Central Michigan University and his Ph.D. in organic chemistry from the Massachusetts Institute of Technology.

Mark Iwicki

Chairman and CEO
Kala Pharmaceuticals

Mark Iwicki has 25 years of experience as a pharmaceutical industry leader managing all stages of drug development and commercialization in multiple therapeutic areas for several high-performance companies. Mark is the Chairman and CEO of Kala Pharmaceuticals and previously was CEO of Civitas Therapeutics which was sold to Acorda Therapeutics in 2014. Prior to joining Civitas, he was President and CEO of Blend Therapeutics, a nanotechnology oncology biotech company. He also served as President and CEO of Sunovion Pharmaceuticals, where he provided leadership for the successful launch of that company, which was created following the acquisition of Sepracor by Dainippon Sumitomo Pharmaceuticals. Mark also previously held key senior leadership roles with Sepracor and Novartis Pharmaceuticals. He currently also sits on the board of directors for Kala Pharmaceuticals, Allergen Research Corporation and Taris Biomedical.

Nikola Trbovic, Ph.D.

Executive Director, WRD and Principal
Pfizer Ventures

Nikola Trbovic, Ph.D. is Executive Director, WRD and Principal at Pfizer Ventures. Nikola is responsible for identifying, evaluating, making and managing equity investments aligned with the future directions of Pfizer. He currently has responsibility for Pfizer's investments in Arrakis, Artios, Cydan, Jnana, Nimbus and Palleon. Prior to his current role, Nikola held responsibilities for R&D technology investments, R&D strategy and early clinical portfolio management in Worldwide Research & Development at Pfizer. Nikola joined Pfizer from McKinsey Co., where he served as an Associate Principal and senior member of the Pharmaceuticals Practice, advising top pharmaceutical, biotech, and healthcare companies on a range of strategy, corporate finance and commercial topics across geographies and therapeutic areas. Nikola received a B.S. in Biochemistry from the University of Frankfurt, Germany, and holds a Ph.D. in Biochemistry and Molecular Biophysics from Columbia University.

Jeb Keiper, M.S., MBA

CEO
Nimbus Therapeutics

Jeb Keiper is the chief executive officer and a board member of Nimbus, having previously served as the chief business officer and chief financial officer. Prior to joining Nimbus, Jeb was VP of Business Development for GlaxoSmithKline (GSK) Oncology and a member of the Oncology Executive team, and responsible for defining and executing the business development strategy for GSK Oncology, including in-licensing transactions, acquisitions, strategic alliances, academic research relationships, alliance management and competitive intelligence. Alongside these responsibilities, Jeb was also named to lead the GSK-Novartis integration of the commercial oncology business valued at $16B. Prior to GSK, Jeb worked in business development at TransForm Pharmaceuticals, as well as for McKinsey. He began his career at Pfizer as a chemist. He received four degrees from the Massachusetts Institute of Technology (MIT): one degree in Chemistry, two degrees in Chemical Engineering and an MBA from the MIT Sloan School of Management.

George P. Vlasuk, Ph.D.

President and CSO
Navitor Pharmaceuticals

Dr. George P. Vlasuk is a scientifically trained executive with nearly 30 years of leadership experience in drug discovery and development at small and large biotechnology and pharmaceutical companies. George currently is President and CSO at Navitor Pharmaceuticals, where he previously served as CEO. Before joining Navitor, he served as CEO of Sirtris, a GlaxoSmithKline Company. Prior to Sirtris, George was Vice President, Metabolic Disease and Hemophilia Research, at Wyeth Pharmaceuticals. George also previously served as Chief Scientific Officer and Executive Vice President of Research and Development at Corvas International, prior to the merger of Corvas and Dendreon Corporation. Earlier in his career, George led a research team at Merck and Co., and was responsible for multiple discovery programs in the field of cardiovascular medicine. George is the author of more than 100 peer-reviewed scientific publications, book chapters and reviews, and 38 issued U.S. and foreign patents.

location

130 Prospect Street, Suite 301
Cambridge, MA 02139
USA

call US

857-999-2009