Director, Facilities

About the job

Nimbus has an outstanding opportunity for an exceptional Director of Facilities to join our growing team! This role will be responsible for Nimbus’ enterprise-wide strategy for facilities and site services and play an integral role in the planning for a likely office move. In addition, this role will manage day-to-day maintenance of facilities, space planning and design, vendor management, and building management liaison. This role will report to our Chief People Officer and work collaboratively with functional leaders, employees, vendors, landlords, and local authorities.

Excellent customer-orientation, communication (written and verbal), organization skills, and creative problem solving are required for success in this position. The candidate must have a high level of professionalism, be capable of working independently with less direct oversight from leadership and be willing to take accountability and ownership of issues and concerns to drive exceptional results.

In this role, you will:

  • Develop and implement a best-in-class facilities operations plan including developing processes, continuous improvement initiatives and tools to enhance rigor within space planning and utilization
  • Direct Nimbus’ Real Estate strategy, incorporating company growth projections and strategic milestones
  • Identify and coordinate with architects and general contractors to build out next space for Nimbus
  • Collaborating with senior leadership and employee stakeholders to space and facility needs that also align with Nimbus’ company culture
  • Plan and manage internal and external project communications, ensuring effective and timely exchange of project information, expectations, and deliverables
  • Oversee all operational and planning aspects of the facilities management including maintenance and repair, custodial, functions and set-ups, and building systems
  • Work with vendors to ensure Nimbus’ facilities are in good working order, including electrical, plumbing, HVAC, furnishings and waste management. Communicate directly with vendors and building management to report facility issues and proactively provide solutions.
  • Continually assess business and operational risk associated with existing and future facilities and develop mitigation and maintenance strategies to address
  • Provide oversight and strategic guidance to team members responsible for delivering services and amenities for Nimbus staff working onsite, including: reception, badge issuance, parking, etc.
  • Manage multiple projects simultaneously to successful outcomes
  • Forecast, track, and manage project budgets, POs, and invoices
  • Coordinate appropriate resources (technical & non-technical) to meet project needs
  • Coordinate teams to implement projects and services with optimal efficiency, on time and within budget
  • Develop effective partnerships and work collaboratively with business partners (HR, Finance, IT, etc.)

These Qualifications Will Help This Role Be Successful

  • 10-15 years of relevant, progressive work experience in Facilities or Operations (required)
  • Demonstrated project management experience and excellent project management and organizational skills to prioritize multiple work streams, deadlines, and balance opposing priorities (required)
  • Strong customer orientation that enables Facilities to align business goals with customer needs and creatively problem solve to determine solutions
  • Excellent interpersonal, negotiation, influence, and communications skill with proven ability to communicate effectively across all departments and levels of the organization
  • Strong expertise and proven track record in process improvement
  • Flexible and adaptable working style that enables work in a fast-paced working environment and work in a diplomatic and tactful manner with others
  • Ability to navigate, problem-solve, execute, and lead in a dynamic, fast-paced and evolving environment

A Snapshot of Nimbus

Our Science

At Nimbus, we design breakthrough medicines. Utilizing our powerful structure-based drug discovery engine, we create potent and selective small molecule compounds targeting proteins that are known to be fundamental drivers of pathology in highly prevalent human diseases and which have proven difficult for other drug makers to tackle. With a decade-plus track record of success, we’ve built a world-class team in both computationally driven drug discovery and early clinical development while continuing to move the needle for patients.

Our Culture

Nimbus is a close-knit company (our employees are Nimbi, if you are curious!) that values a fast-paced, entrepreneurial, intellectual-stimulating, and collaborative environment. We live by our Core Values: Integrity, a Passion for Excellence, Teamwork, and Authentic Communication and strive to build a community where we bring out the best in each other professionally and personally.

Our Company

Founded in 2009, Nimbus is a private, growing biotechnology company headquartered in Cambridge, Massachusetts. Learn more about us by going to www.nimbustx.com

Join Nimbus. We are making a difference and you can too.

Nimbus is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Nimbus does not accept unsolicited resumes from any source other than directly from candidates.

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Associate Director / Director, Translational Biology

About the job

Nimbus has an outstanding opportunity for an exceptional translational scientist with experience in early discovery and clinical development in the fields of oncology and/or immunology to join our team. The Associate Director / Director of Translational Biology will report to our Head of Translational Biology.

In this role, you will:

  • Lead efforts to develop and implement strategies for clinical biomarker testing, indication assessment and expansion, patient stratification, combination therapy, mechanism of action studies, and drug candidate differentiation
  • Identify pharmacodynamic assays for utility in pre-clinical and clinical setting; help define PK/PD/efficacy relationships and test patient selection strategies
  • Develop clinical biomarker testing strategies for clinical trials, collaborate with clinical team on all aspects of clinical assay development and operations, and communicate translational designs and findings with clinical investigators
  • Lead primary analyses of pre-clinical and clinical exploratory translational biomarker studies
  • Author and review the translational sections of regulatory documents as well as scientific/clinical publications, and represent Nimbus Therapeutics to present translational findings at scientific congresses and investigator meetings
  • Manage relationships and scientific studies with diverse CRO’s, external collaborations with KOLs, and clinical investigators aimed at gaining a deeper understanding of MOA and the development of patient stratification or pharmacodynamic biomarkers
  • Contribute to early development of the Nimbus discovery pipeline as a biology team representative for novel target programs and/or new target identification efforts
  • Additional responsibilities as needed and directed

These Qualifications Will Help This Role Be Successful

Required qualifications:

  • Ph.D. in biochemistry, cell biology, bioinformatics, pharmacology, medical science, or related field
  • At least five years of drug development experience in industry, including direct contributions to early drug development programs
  • Experience in leading biomarker testing in clinical trials for oncology and/or immunology drug development, including analysis of genome-wide ‘omics datasets
  • Outstanding track record of scientific achievement and excellent soft skills
  • Excellent verbal and written communication and organizational skills with demonstrated success in leading projects and interacting with cross functional teams
  • Ability to navigate, problem-solve, execute, and lead in a dynamic, fast-paced and evolving environment

Additional preferred qualifications include:

  • Experience in managing scientific teams and research in an externalized setting
  • Experience with small molecule drug development and IND submissions

A Snapshot of Nimbus

Our Science

At Nimbus, we design breakthrough medicines. Utilizing our powerful structure-based drug discovery engine, we create potent and selective small molecule compounds targeting proteins that are known to be fundamental drivers of pathology in highly prevalent human diseases and which have proven difficult for other drug makers to tackle. With a decade-plus track record of success, we’ve built a world-class team in both computationally driven drug discovery and early clinical development while continuing to move the needle for patients.

Our Culture

Nimbus is a close-knit company (our employees are Nimbi, if you are curious!) that values a fast-paced, entrepreneurial, intellectual-stimulating, and collaborative environment. We live by our Core Values: Integrity, a Passion for Excellence, Teamwork, and Authentic Communication and strive to build a community where we bring out the best in each other professionally and personally.

Our Company

Founded in 2009, Nimbus is a private, growing biotechnology company headquartered in Cambridge, Massachusetts. Learn more about us by going to www.nimbustx.com

Join Nimbus. We are making a difference and you can too.

Nimbus is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Nimbus does not accept unsolicited resumes from any source other than directly from candidates.

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Senior Director of Contracts, Legal

About the job

Nimbus has an outstanding opportunity for an exceptional Senior Director of Contracts, Legal to join our team. The Senior Director of Contracts, Legal will be responsible for independently overseeing the contracts function in support of Nimbus’ discovery and development efforts. This individual will oversee a wide variety of contracts with CROs in the US and outside the US. This role will report to our Chief Business Officer and collaborate cross-functionally in tandem with the procurement team.

In this role, you will:

  • Review and negotiate Confidential Disclosure Agreements, Master Service Agreements, Master Consulting Agreements, Consulting Appendices, Amendments, Clinical Contracts and other agreements in accordance with Nimbus’ business structure, legal standards and project timelines
  • Approve all contracts pre-signature
  • Assist with, serve as resource, and review BD Contracts
  • Serve as contact for legal contract questions within and outside the company
  • Interface with external contracts attorneys
  • Collaborate in the development and maintenance of processes and procedures (templates, tools, documents, etc.) internally to standardize work flow and manage risk. Communicate processes/procedures to internal team as needed
  • Ensure contract repository is accurate and up to date
  • Maintain relationships with counterparts at CROs/vendors; address or delegate vendor queries and issues
  • Understand vendor service offerings and stay current with industry trends and the legal and regulatory landscape
  • Partner with Senior Contracts / Procurement Specialists on training colleagues on contracts processes & procedures
  • Complete special projects including supporting deal transactions and collaborating on department-wide or company-wide initiatives, as requested

These Qualifications Will Help This Role Be Successful

  • A J.D or a Bachelor’s degree and minimum of 8-10 years experience drafting, negotiating, and executing contracts in the biopharmaceutical industry
  • Thorough understanding of the contract process, including contract evaluation, negotiation, approval and execution
  • Knowledge of the Drug Discovery and Development process
  • Demonstrated business acumen; skilled at integrating legal advice with business acumen and sound judgment
  • Demonstrated ability to multi-task, problem-solve and operate in a fast-paced environment
  • Experience working directly with CROs
  • Familiarity with Conga Contracts Management software systems (preferred) and Office 365 Suite experience (required)
  • Outstanding organizational, written and verbal communication skills, as well as strong attention to detail
  • Preferred familiarity with Compliance/Quality Systems

A Snapshot of Nimbus

Nimbus is a ~40 person, biotechnology company located in the thriving biotech hub of Cambridge, Massachusetts. We transform drug development by integrating computational drug discovery techniques, a cutting-edge computational chemistry platform and other advanced technologies to design breakthrough medicines for patients.

We focus on promising targets in metabolic disease, oncology and inflammation. These include both emerging and well-validated targets that have proven intractable to others in the pharmaceutical and biotechnology industry.

Nimbus offers a fast-paced, entrepreneurial, team-focused work environment. The culture is intellectually stimulating, flexible and results-oriented. Joining our team of 30+ people offers significant opportunities to grow professionally and personally.

We also offer a top-notch benefits package (health, dental, life, vacation, and employer 401K contribution ). Being part of Nimbus (a Nimbi, if you’re curious), allows you to become part of a small close-knit professional team that strives to bring out the best in each other by working hard and having fun together.

Join Nimbus. We are making a difference and you can too.

Find out more at www.NimbusTx.com

Nimbus is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Nimbus does not accept unsolicited resumes from any source other than directly from candidates.

APPLY NOW

Associate Director/Director, Project Management

Role & Responsibilities 

Reporting to the Senior Director of Project Management, the Associate Director/Director, Project Management will manage key project(s), primarily within preclinical/clinical development in the therapeutic areas of immunology/inflammation, oncology, and metabolic diseases at Nimbus. We are seeking a highly motivated, collaborative, results-oriented individual with the creativity, resourcefulness, and flexibility to excel in a growing company.

This individual will:

  • Partner with Project Leader(s) to optimize the Project Team’s effectiveness and decision making; facilitate team building and communication, create and drive timelines to keep project(s) on schedule
  • Manage the planning and day-to-day execution of projects, ensuring that deliverables are achieved and milestones are met; provide cross-functional activity tracking/oversight and contribute to development of longer term strategy for the program in partnership with the Project Leader(s) and R&D management
  • Establish and maintain functionally integrated project plans/timelines; accurately track and provide timely reporting on progress
  • Facilitate continuous identification of opportunities, risks/mitigations, and resolution with Project Team input
  • Coordinate development of strategic project plans with Project Team input
  • Schedule, organize, and drive team meeting(s): prepare and distribute agendas/minutes; identify and track decisions and action items, escalate areas of concern as appropriate
  • Collaborate with Project Leaders, Finance, and as appropriate Department Heads to develop and update project budgets
  • As applicable, coordinate resources, timelines, and deliverables with other Project Managers
  • Help manage and coordinate program related CRO contracts and work orders

The Qualifications We’re Seeking

  • Must have at 5-7+ years experience in R&D in pharma or biotech (some experience with small to medium-sized companies is preferred), with a minimum of 8 years in project management on interdisciplinary or cross-functional project teams
  • Experience in small molecule development required
  • BA/BS in a scientific discipline is required; an advanced degree (PhD, MS, MBA, MD) in a field relevant to drug development is desirable
  • Alliance management experience desirable
  • Experience in oncology clinical development desirable
  • Extensive experience with programs in preclinical/clinical development required; involvement in regulatory submissions, including INDs/CTAs, and regulatory agency interactions is desirable; some experience with discovery-stage research is desirable
  • Must have a proactive mindset with strong leadership, facilitation, teamwork, influence management, organizational skills, and ability to work independently
  • Excellent interpersonal skills required, along with an ability to develop important relationships with key stakeholders and work collaboratively, skilled in conflict management/negotiation
  • Highly proficient in utilizing project management best practices, project planning, and facilitative decision-making. Skilled in goal setting, prioritization, and time management
  • Broad understanding of biopharmaceutical drug development, including working knowledge of relevant ICH, GLP, and GCP guidance and regulations
  • Experience managing collaborations with consultants, pharmaceutical partners, CROs, and other external organizations is desirable
  • Excellent written and oral communication and information management skills; ability to interact with a diverse groups of individuals
  • Skilled with Microsoft Office Suite and Microsoft Project
  • Project Management Certification (PMP or equivalent)

A Snapshot of Nimbus

Nimbus is a ~40 person, biotechnology company located in the thriving biotech hub of Cambridge, Massachusetts. We transform drug development by integrating computational drug discovery techniques, a cutting-edge computational chemistry platform and other advanced technologies to design breakthrough medicines for patients.

We focus on promising targets in metabolic disease, oncology and inflammation. These include both emerging and well-validated targets that have proven intractable to others in the pharmaceutical and biotechnology industry.

Nimbus offers a fast-paced, entrepreneurial, team-focused work environment. The culture is intellectually stimulating, flexible and results-oriented. Joining our team of 30+ people offers significant opportunities to grow professionally and personally.

We also offer a top-notch benefits package (health, dental, life, vacation, and employer 401K contribution ). Being part of Nimbus (a Nimbi, if you’re curious), allows you to become part of a small close-knit professional team that strives to bring out the best in each other by working hard and having fun together.

Join Nimbus. We are making a difference and you can too.

Find out more at www.NimbusTx.com

Nimbus is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Nimbus does not accept unsolicited resumes from any source other than directly from candidates.

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Clinical Research Scientist

Role & Responsibilities 

Reporting to our VP, Early Clinical Development, the Clinical Research Scientist will be a key member of the Discovery team, supporting the activities associated with clinical studies. The person in this role will be responsible for designing, implementing, and undertaking clinical trials during the research process. They will coordinate with the other members of the research team and be responsible for liaising with the senior leadership team, outside vendors, and other clinical investigators.

More specifically, the person in this role will:

  • Review the scientific data and develop product knowledge to understand and communicate the relevant information for 1 or more clinical studies
  • Develop and review various study protocols with minimal guidance including writing, reviewing, adjudication/resolution of cross functional comments, and ensuring a high quality final document
  • Prepare and present the reports and presentations on the various findings of the clinical research
  • Provide regular updates on the progress of the clinical research to the broader Discovery team, senior leadership team, and other relevant functions
  • Regularly review the information to check safety procedures, efficiency, and the lab data accuracy and correctness
  • Review and validate clinical study reports (CSRs) with a thorough understanding of the connection between the data and the CSR
  • Contribute to, coordinate, and review regulatory documents, Consent Forms (ICF), and other relevant materials
  • Collaborate with all study team members including Clinical, Clinical Operations, Drug Safety, Regulatory Affairs and CRO / external vendors

These Qualifications Will Make This Role Successful

  • Bachelor’s degree in life sciences or health-related field with an advanced degree such as a Masters, PharmD, PhD in biological / pharmaceutical science, or MD
  • Experience across multiple therapeutic areas, including oncology and/or immunology/inflammation (preferred)
  • Proficient knowledge and skills to support program specific data review, trend identification, data interpretation
  • Proficient in Medical Terminology and medical writing skills
  • Knowledge on ICH, GCP, and other relevant regulatory guidelines
  • Proven ability to analyze clinical information succinctly and efficiently with strong written communication – especially as it relates to developing clinical protocols, assessing the quality of data, and presenting trial results
  • Excellent interpersonal and decision-making skills with demonstration of innovation, drive, energy and enthusiasm to deliver key objectives in a timely manner.
  • Ability to navigate, problem-solve, execute, and lead in a dynamic, fast-paced and evolving environment
  • An outstanding track record of strong communication, presentation, analytic and strategic capabilities and ability to effectively collaborate with medical experts

A Snapshot of Nimbus

Nimbus is a ~ 40 person, biotechnology company located in the thriving biotech hub of Cambridge, Massachusetts. We transform drug development by integrating computational drug discovery techniques, a cutting-edge computational chemistry platform and other advanced technologies to design breakthrough medicines for patients.

We focus on promising targets in metabolic disease, oncology and inflammation. These include both emerging and well-validated targets that have proven intractable to others in the pharmaceutical and biotechnology industry.

Nimbus offers a fast-paced, entrepreneurial, team-focused work environment. The culture is intellectually stimulating, flexible and results-oriented. Joining our Team offers significant opportunities to grow professionally and personally.

We also offer a top-notch benefits package (health, dental, life, vacation, and employer 401K contribution). Being part of Nimbus (a Nimbi, if you’re curious), allows you to become part of a small close-knit professional team that strives to bring out the best in each other by working hard and having fun together (company lunches and outings, running, rocking and even bowling from time to time!)

Join Nimbus. We are making a difference and you can too.

Nimbus is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Nimbus does not accept unsolicited resumes from any source other than directly from candidates.

APPLY NOW